Overview Information Ergot is a fungus that grows on rye and less commonly on other grasses such as wheat. This medication, a combination of several drugs that belong to a group of drugs called ergoloid mesylates, is used to relieve the signs and symptoms of decreased mental capacity due to the aging process. It is characterized by spasms, diarrhea, head aches, vomiting etc. Alkaloid, any of a class of naturally occurring organic nitrogen-containing bases. 2 This group of drugs has been called many things: ergots, ergot derivatives, and ergot alkaloids. Methergin is the brand name of the drug that has been derived from Ergot and is used to stop post natal bleeding 10. ergotamine Ergot on rye 11. ergotamine tartrate: [Érgotâ²ÉmÄn] a vasoconstrictor that binds to several receptor populations (e.g., alpha-adrenergic, dopamine, serotonin) and, depending upon the receptor, can be an agonist or antagonist. Ergotamine also affects blood flow patterns that are associated with certain types of headaches.. Ergotamine is used to treat a migraine type headache.. It was approved by the FDA in 1951. It works by narrowing the blood vessels around the brain. Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). Examples of affected drugs include certain alpha blockers (such as alfuzosin, silodosin, tamsulosin), certain benzodiazepines (such as midazolam), dronedarone, ergot alkaloids (such as ergotamine, dihydroergotamine), pimozide, quinidine, rivaroxaban, sirolimus, certain "statin" drugs (such as simvastatin, lovastatin), among others. Ergotamine selectively binds and activates serotonin 1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, thereby resulting in vasoconstriction and reducing the blood flow in cerebral arteries that may lead to relieve of vascular headaches. In plants, their function is still mostly unknown. Dobutrex. The generic Isoxsuprine is manufactured by one company. name Parlodel) i s a non-hor monal, ... (brand names Caberlin, Lysergide (LSD) is a semi-synthetic hallucinogen, and is one of the most potent drugs known.Recreational use became popular between the 1960s to 1980s, but is now less common. Methylergonovine is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. Methylergonovine belongs to a class of drugs called ergot alkaloids. Triptans . For more information on drug types and brand names, click or tap on the â?â tooltip to the right of each drug classification. It is a nasal solution used to help relieve migraine headaches. DOSAGE AND ADMINISTRATION. Methylergonovine is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. The most commonly used contain aspirin or paracetamol combined with codeine, caffeine and/or an anti-emetic. In patients receiving ergot alkaloids Azithromycin should be avoided because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system. They are also said to increase blood flow to the brain and generally increase cognitive abilities though the evidence is contradictory on these points. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Ergot alkaloids are produced by species of Claviceps, especially C. purpurea. ... Calpol etc. Well-known alkaloids include morphine, strychnine, quinine, ephedrine, and nicotine. Ergot Derivatives: Dosing, Uses, Side Effects, Interactions, Patient Handouts, Pricing and more from Medscape Reference. When This Medicine Should Not Be Used: You should not use this medicine if you are pregnant or have had an allergic reaction to ergotamine tartrate. Dihydroergotamine belongs to the group of medicines called ergot alkaloids. Pharmacology. Brand Name(s): There may be other brand names for this medicine. The visible symptom of ergot is the replacement of the cereal kernel with dark purple sclerotia (or ergot bodies).